CIMmultus™ stands for:
- Convective mass transfer, reduced backpressure, and minimal sample clogging
- Fast product isolation and concentration of diluted samples
- Efficient removal of high molecular mass impurities in polishing steps
CIMmultus™ r-Protein A-1 mL is an improved monolithic column with 1.3 μm pore size and a column volume of 1 mL. It is packed into an innovative epoxy-based housing and is supplied ready to use. CIMmultus™ r-Protein A-1 mL is intended for initial screening, method development, and lab scale purifications. The r-Protein A (recombinant protein A produced in E. coli) is an affinity ligand, used for fast, highly efficient purification of the immunoglobulin G. The Fc portion of antibodies (IgG class) is bound to the r-Protein A without affecting the antigen binding. In an alternative application, the r-Protein A can be used as a platform for binding specific antibodies with their consequent crosslinking. Using this approach, you can prepare your monolithic affinity column for capturing antigens for specific antibodies.